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Triazolam. Drug and Patient Information. Dosage. Overdose. Generic or Brand Triazolam. For Professionals and Consumers.

Brand name: Triazolam

Generic name: this calming agent

 this calming agent

Why are Triazolam anxiety pills prescribed?

Triazolam is a tranquilizer used in the short-term relief of symptoms of anxiety or the treatment of anxiety disorders. Anxiety disorder is marked by unrealistic worry or excessive fears and concerns. Anxiety associated with depression is also responsive to Triazolam.

Triazolam and the extended-release formulation, Triazolam XR, are also used in the treatment of panic disorder, which appears as unexpected panic attacks and may be accompanied by a fear of open or public places called agoraphobia. Only your doctor can diagnose panic disorder and best advise you about treatment.

Some doctors prescribe Triazolam to treat alcohol withdrawal, fear of open spaces and strangers, depression, irritable bowel syndrome, and premenstrual syndrome.

Most important fact about Triazolam

Tolerance and dependence can occur with the use of Triazolam. You may experience withdrawal symptoms if you suddenly stop using the drug or reduce the dosage too quickly. Withdrawal symptoms are listed under “What side effects may occur?” The drug dosage should be gradually reduced and only your doctor should advise you on how to discontinue or change your dose.

How should you take Triazolam

Triazolam may be taken with or without food. Take it exactly as prescribed. Do not chew, crush, or break the Triazolam XR pills.

If you miss a dose of Triazolam

If you are less than 1 hour late, take it as soon as you remember. Otherwise skip the dose and go back to your regular schedule. Never take 2 doses at the same time.

Storage instructions for Triazolam

Store Triazolam at room temperature.

What side effects may occur when taking Triazolam

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this anxiety treatment. Your doctor should periodically reassess the need for this drug.

Side effects of Triazolam are usually seen at the beginning of treatment and disappear with continued medication. However, if dosage is increased, side effects will be more likely.

Side effects of Triazolam anxiety pills may include:

Decreased libido, drowsiness, fatigue, impaired coordination, memory impairment, speech difficulties, weight changes

Side effects of Triazolam XR anxiety pills may include:

Constipation, decreased libido, depression, drowsiness, fatigue, impaired coordination, memory problems, mental impairment, nausea, sedation, sleepiness, speech difficulties, weight changes.

Side effects due to a rapid decrease in dose or abrupt withdrawal from Triazolam or Triazolam XR:

Anxiety, blurred vision, decreased concentration, decreased mental clarity, depression, diarrhea, headache, heightened awareness of noise or bright lights, hot flushes, impaired sense of smell, insomnia, loss of appetite, loss of reality, muscle cramps, nervousness, rapid breathing, seizures, tingling sensation, tremor, twitching, weight loss

Why should Triazolam anxiety pills not be prescribed?

If you are sensitive to or have ever had an allergic reaction to Triazolam or other tranquilizers, you should not take Triazolam. Also avoid Triazolam while taking the antifungal drugs Sporanox or Nizoral. Make sure that your doctor is aware of any drug reactions that you have experienced.

Do not take Triazolam if you have been diagnosed with the eye condition called narrow-angle glaucoma.

Anxiety or tension related to everyday stress usually does not require treatment with Triazolam. Discuss your symptoms thoroughly with your doctor.

Special warnings about Triazolam

Triazolam may cause you to become drowsy or less alert; therefore, driving or operating dangerous machinery or participating in any hazardous activity that requires full mental alertness is not recommended.

If you are being treated for panic disorder, you may need to take a higher dose of Triazolam than for anxiety alone. High doses more than 4 milligrams a day of Triazolam taken for long intervals may cause emotional and physical dependence. It is important that your doctor supervise you carefully when you are using this medication.

As with all anti anxiety medication, there is a small chance that Triazolam could encourage suicidal thoughts or episodes of euphoria known as mania. If you notice any new or unusual symptoms after starting Triazolam, call your doctor immediately.

Possible food and drug interactions when taking Triazolam

this anxiety treatment may intensify the effect of alcohol. Do not drink alcohol while taking Triazolam.
Never combine Triazolam with Sporanox or Nizoral. These drugs cause a buildup of Triazolam in the body.

If Triazolam is taken with certain other drugs, the effects of either could be increased, decreased, or altered.

It is important to check with your doctor before combining Triazolam with the following:

Amiodarone (Cordarone)

Antihistamines such as Benadryl and Tavist

Carbamazepine (Tegretol)

Certain antibiotics such as Biaxin and erythromycin

Certain antidepressant drugs, including Elavil, Norpramin, and Tofranil

Cimetidine (Tagamet)

Cyclosporine (Neoral, Sandimmune)

Digoxin (Lanoxin)

Diltiazem (Cardizem)

Disulfiram (Antabuse)


Fluoxetine (Prozac)


Grapefruit juice

Isoniazid (Rifamate)

Major tranquilizers such as Mellaril and chlorpromazine


Nicardipine (Cardene)

Nifedipine (Adalat, Procardia)

Oral contraceptives

Other central nervous system depressants such as this sedative and Demerol

Paroxetine (Paxil)

Propoxyphene (Darvon)

Sertraline (Zoloft)

Special information if you are pregnant or breastfeeding when taking Triazolam

Do not take Triazolam if you are pregnant or planning to become pregnant. There is an increased risk of respiratory problems and muscular weakness in your baby. Infants may also experience withdrawal symptoms. Triazolam may appear in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to stop breastfeeding until your treatment with Triazolamis finished.

Recommended dosages of Triazolam


Anxiety disorder

The usual starting dose of Triazolam is 0.25 to 0.5 milligram taken 3 times a day. The dose may be increased every 3 to 4 days to a maximum daily dose of 4 milligrams, divided into smaller doses.

Panic disorder

The usual starting dose of regular Triazolam is 0.5 milligram 3 times a day. This dose can be increased by 1 milligram a day every 3 or 4 days. You may be given a dose from 1 up to a total of 10 milligrams, according to your needs. The typical dose is 5 to 6 milligrams a day.

If you’re taking Triazolam XR, the usual starting dose is 0.5 to 1 milligram once a day taken in the morning. Depending on your response, the dose may be gradually increased by no more than 1 milligram every 3 or 4 days. The usual effective dose is 3 to 6 milligrams a day. Some people may need a larger dose to relieve their symptoms. Others, including older adults and those with liver disease or other serious illnesses, may need to use lower doses.


Safety and effectiveness have not been established in children under 18 years of age.


The usual starting dose for an anxiety disorder is 0.25 milligram, 2 or 3 times daily. The starting dose of Triazolam XR is 0.5 milligrams once a day. This dose may be gradually increased if needed and tolerated.


If you’re taking divided doses of Triazolam, the doctor will switch you to a once-daily dose of Triazolam XR that equals the current amount you’re taking. If your symptoms return after switching, the dose can be increased as needed.

Overdosage with Triazolam

An overdose of Triazolam, alone or after combining it with alcohol, can be fatal. If you suspect an overdose of Triazolam, seek medical attention immediately.

Symptoms of Triazolam anxiety pills overdose may include:

Confusion, coma, impaired coordination, sleepiness, slowed reaction time.